Does anyone think that due to the super long half life previous doses massively potentiate later doses leading to the impression of reverse tolerance when in actuality it’s more so because the last dose reactivated to some extent previous dose due to the half life? What do you all think?
So I recently accidentally purchased a vape that has a “nicotine substitute” (6-Methyl Nicotine) in it.
This chemical is potentially more damaging to the lungs when vaped or inhaled than regular nicotine and also 2-5x more potent, and thus even more addictive than nicotine itself lol
So my first time I took 3 puffs and felt a familiar nicotine buzz only stronger and very slightly different feeling compared to nicotine, there was noticeable stimulation (felt more alert and energized for sure) and the duration seemed longer than regular nicotine as well. while it is a pretty unknown research chemical with potentially negative side effects we aren’t even aware of yet, I think it’s pretty cool you can legally try a very potent RC nicotine analogue like this, although I certainly am not about to recommend it as a daily replacement since we don’t know the possible negatives, it’s potentially more toxic than nicotine and the LD50 is concerningly 1/3 of nicotine itself but the “buzz” is also slightly stronger and more enjoyable than regular nicotine as well so I guess you can decide if the risk is worth it to you or not.